Leslie Baumann made a recent article in the Blog This paper and other papers cited past few days I also look carefully, I think the trends and conclusions of this study deserve close attention, but also unnecessary products immediately asserted VA can not be used, the key is whether the art of products using the VA to make it the benefit of the skin.
Craig A. Elmets MD from the [Papers] in my view, the key to the increased risk of death should be [overdose] of 0.1% Tretinoin, the text explicitly mentioned in the 2 - 6 years of twice daily use of 0.1% Tretinoin, VA such a high concentration of acid in the use of twice daily home life and death itself is a bit crazy at the givers, and the outline did not say there is no long-acting broad spectrum of subjects UV-protection products with the (yet to see the full paper is mentioned), the use of VA acid UV protection, while sure to be a proper common sense, so this test the conclusions obtained unnecessary panic, but concern and negative, as far as I know most people regardless of DeVito, tazarotene, Duff Man, VA aldehydes, alcohols, esters are used once in the evening, many people also understand that intermittent use to prevent excessive metabolic horny reason, more than 2 consecutive years, not many people, coupled with the knowledge of sun awareness and popularity of the increase in risk of death should also unnecessary worry too much about the other article also mentioned that this experiment in 95 subjects % male, in reality, regardless of skin care products containing VA is certainly more women than men, the paper declared himself on this matter how this effect is not clear. Baumann doctors also reminded that no matter in what VA Class Beta Carotene services or products people do not smoke, this is a common sense should have knowledge of, and in fact, I would also like to remind an increased attention to the working and living environment, whether there is risk of passive smoking.
both How do these studies make me more believe that I have been advocating a low concentration of VA acid (0.025%) or VA alcohol (0.075%) Long-term use or partial use of the interval is feasible, even if no increase in risk of death that I do not advocate one over-stimulating the metabolism skin, the risk of death if the [longitudinal study] Confirmation of the results of a VA concentration of acid is not safe no matter what it be a different matter, at least Renova (0.05% VA acid) in the past 14 years is no clear record of death (no effect but many records), is used once per day plus long-acting broad spectrum of people who will not need UV protection to over-worry about, according to my personal use is what derivatives regardless of the concentration VA products use up to 4-5 times per week, in the middle have a definite interval, together with my other ingredients with the flexibility to consider, the effect is not better than continuous use of 0.1% A crazy man acid difference, both to improve the pores, or skin compactness, color, and I think that due to the safety and effectiveness, of course, I kept looking for it also has been the replacement of components or minimize its use concentration.
Retinol products containing high concentrations of how to determine it VA acid may reach the same effect? Skinmedica Retinol Complex according to the official description of the product compound of 1.5% of the VA and the VA ester alcohol, the equivalent of 0.65% Total Retinoids, about 40% conversion rate, although different products with different formulations the conversion rate will not be exactly the same, so this value only for other product information: Anthony Logistics Anti Aging Vitamin A Treatment (10% Retinyl Palmitate / 3-5% Retinol calculated according to the actual conversion is slow, in short, a person must have enough crazy), PTR un-wrinkle night (2% Retinol, PTR also has been out a 5% pure Retinol products, probably because of side effects of too much off the assembly line), SkinCeuticals 0.5% or 1% Retinol, June Jacobs Brightening Serum With Retinol (1% Retinol) can be roughly equivalent to calculate the number of VA acid, Neutrogena and RoC Retinol products, most of the concentration of the product does not exceed 0.1%, Avene home A aldehyde [theory] A high conversion rate in alcohol, [personal that] the majority of the Avene product formulations can reach 60% conversion rate.
by the response of some clever person that summarize the methods used A acid:
Hui mm: DeVito (0.1%), large green bean + Phoenix about 5 times the amount of glycerol / Hydra is not oil
Kenji: music for the rose hip oil + (0.1% tazarotene) / mild partial oil
axmf: DeVito (0.1%) + 3 times urea ester / moisturizing oily
my own way: DeVito (0.1%) + anhydrous cream or cream / Refreshing dry
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